Z. Min
2008
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Journal
Pharmaceutical and Clinical Research
Abstract
Objective:To establish the method for microbial limit tests of dihydralazine sulfate.Method: To determine the recovery of the test bacteria which was in the dihydralazine sulfate,using five kinds of the test bacteria.The test group and the negative compared group were used to verificate the method of examing the control bacteria.Results: Using the centrifugalization-medium dilution and the conventional method,the recovery of those five kinds of bacterias was above 70%.The method of centrifugalization could effectively check the Escherichia coli out.Conclusions: The dihydralazine sulfate has a strong antibacterial effect.The number of bacteria was counted by the centrifugalization-medium dilution method;the number of fungi and yeast was counted by the conventional method;the control bacteria was detected by the centrifugalization method.