Guannan Wang, Lin Yang, Li-he Zhang
Mar 4, 2011
Citations
0
Influential Citations
19
Citations
Journal
The Journal of organic chemistry
Abstract
A versatile and concise synthesis of N-alkylated 1,4-dideoxy-1,4-imino-D-arabinitol and 1,4-dideoxy-1,4-imino-L-xylitol derivatives is described. These were prepared using pseudohemiketal lactams as key intermediates, which in turn were obtained from sucrose. The key intermediates were prepared by a diastereospecific tandem reaction which facilitated the introduction of various substituents on the nitrogen atom of the iminosugars.