V. Hegde, J. Renga, J. Owen
Mar 4, 2001
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A versatile two-step synthesis of 2-alkyl-4-aminopyridines from commercially available cis -1-methoxy-1-buten-3-yne is described. Acylation of the yne derivative followed by amination and cyclization in ammonia produced the desired substituted pyridines in high yield.