R. Murashige, Yoko Ohtsuka, Kazuki Sagisawa
Jun 3, 2015
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
Versatile intramolecular Friedel–Crafts reaction of 1-(2-iso-cyanatoethyl)benzene derivatives was established by using trifluoromethanesulfonic acid as a catalyst and solvent. This methodology has been applied to the substrates with strong electron-withdrawing group. Furthermore, using the Friedel–Crafts product as a common synthetic intermediate, synthesis of several isoquinoline derivatives was also successful.