F. Cambeiro, S. López, J. Varela
Jun 2, 2014
Citations
0
Influential Citations
54
Citations
Journal
Angewandte Chemie
Abstract
A novel synthesis of 2-vinyldihydropyrans and dihydro-1,4-oxazines (morpholine derivatives) from alkynals and alkynones has been developed. The cyclizations require a mild generation of catalytic ruthenium carbenes from terminal alkynes and (trimethylsilyl)diazomethane followed by trapping with carbonyl nucleophiles. Mechanistic aspects of the new cyclizations are discussed.