P. Hongmanee, K. Rukseree, B. Buabut
Dec 18, 2006
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0
Influential Citations
56
Citations
Quality indicators
Journal
Antimicrobial Agents and Chemotherapy
Abstract
ABSTRACT The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 μg/ml. The MIC50 and MIC90 were 0.125 and 0.25 μg/ml, respectively. These indicate that cloxyquin exhibited good antituberculosis activity, even for multidrug-resistant isolates.