Y. Balducci, G. Bodey
Jul 1, 1974
Citations
0
Influential Citations
2
Citations
Quality indicators
Journal
The Journal of antibiotics
Abstract
Kitasamycin was tested in vitro against 214 clinical isolates of gram-positive cocci and its activity compared to minocycline, cephalothin, erythromycin, clindamycin and dicloxacillin. All isolates of Streptococcus pyogenes were inhibited by 0.39μg/ml. At a concentration of 1.56μg/ml, kitasamycin inhibited all isolates of Diplococcus pneumoniae, 98% of isolates of Staphylococcus aureus sensitive to penicillin G and 99% of isolates of Staphylococcus aureus resistant to penicillin G. Most of the other antibiotics were as active or more active than kitasamycin against gram-positive cocci.