S. Manap, H. Yüksek, Zeynep Eki̇nci̇
Apr 30, 2022
Citations
0
Influential Citations
0
Citations
Journal
Afyon Kocatepe University Journal of Sciences and Engineering
Abstract
In this study, nine novel 3-alkyl-4-[3-methoxy-4-(p-nitrobenzoxy)-benzylideneamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) were synthesized from the reactions of 3-alkyl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) with 3-methoxy-4-(p-nitrobenzoxy)-benzaldehyde (2), which was synthesized by the reaction of 3-methoxy-4-hydroxybenzaldehyde with p-nitrobenzoyl chloride by using triethylamine. The structures of novel compounds were established from IR, 1H NMR and 13C NMR spectral data. In addition, in vitro antibacterial capacities of the new compounds were determined against six bacteria by mains of agar well diffusion method. Furthermore, newly synthesized compounds antioxidant capacities were performed by three different methods.