M. Kobisch, P. Perreau, F. Génin
1984
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Quality indicators
Journal
Annales De Zootechnie
Abstract
The effect of spiramycin on Mycoplasma hyopiieitnioiiiae was checked. In vitro, the M.I.C. of spiramycin on two bacterial strains in a liquid medium were 0.173 and 0.347 !g/ml (expressed in spiramycin W.H.O. standard containing 3 200 IU/mg). On the other hand, the therapeutic efficiency of spiramycin (embonate) was controlled in SPF piglets experimentally infected with Mycoplasma hyopl1eumoniae. The antibiotic was administered in a medicated feed with 250 ppm from the age of 25 days during 10 days. The animals were contaminated at the age of 16 days. No clinical, anatomo-pathological, histo-pathological and serological signs were observed on 5 treated animals out of 7. But, all the infected and non treated animals exhibited all these signs. health