Sylvia R. M. Lima, V. F. V. Junior, Herick B. Christo
Nov 1, 2003
Citations
5
Influential Citations
119
Citations
Quality indicators
Journal
Phytotherapy Research
Abstract
Copaiba oil resin (COR) obtained from Copaifera multijuga Hayne has been used in popular medicine as an antinflammatory and for the treatment of bronchitis, ulcers and cancer. The aim of this study was to evaluate the action of COR and its fractions on the inhibition of lung metastasis and tumour growth induced by B16F10 melanoma cells in mice and cytotoxicity in vitro using Trypan Blue exclusion method and MTT conversion.