A. Ivaska, Y. Vaneesorn, I. E. Davidson
Dec 1, 1980
Citations
0
Influential Citations
10
Citations
Journal
Analytica Chimica Acta
Abstract
Abstract Some 2-thiobarbituric acid and thioamide drugs are determined voltammetrically in a flow-through cell. Both direct oxidation in the d.c. mode and cathodic stripping on a mercury-coated glassy carbon electrode are examined for the determination of these drugs. The thiobarbiturie acids can be determined by both methods; the linear range covers 1–2 orders of magnitude with a detection limit in the range 10 -3 –10 -6 M depending on the method used and the compound. The thioamides do not plate satisfactorily on the mercury film when operated in the on-line mode and can only be determined by the d.c. anodic oxidation method; the linear range covers at least two orders of magnitude with a detection limit of 5×10 -8 –5×10 -7 M depending on the compound.