S. Dalal, S. Rana, K. Sastry
Dec 31, 2008
Citations
0
Influential Citations
8
Citations
Quality indicators
Journal
The Internet journal of microbiology
Abstract
Wedelolactone is a naturally occurring coumestan isolated from aerial parts of Eclipta alba. E. alba is used as a traditional medicine for the treatment of several diseases. The antimicrobial activity of wedelolactone was evaluated using minimum inhibitory concentration and agar well diffusion method. The compound exhibited good activity against Staphylococcus epidermidis and Salmonella typhimurium. The MIC test showed the growth inhibition of S. epidermidis at a concentration of 15.0 μg/ml, ZOI 10.24 mm and of S. typhimurium at a concentration of 25.0 μg/ml, ZOI 9.16 mm. Escherichia coli was the most resistant bacterial strain. These results suggest the wedelolactone as a promising antimicrobial agent.