F. P. Arcanjo, Cecília Costa Arcanjo, O. S. Amâncio
Dec 1, 2011
Citations
1
Influential Citations
10
Citations
Quality indicators
Journal
Journal of tropical pediatrics
Abstract
OBJECTIVE This study analyses the impact of weekly iron supplementation with ferrous sulphate heptahydrate (FeSO4) in 5-year-olds compared with placebo, on hemoglobin (Hb) and hematocrit (Ht) values and anemia. DESIGN The study concerns a cluster-randomized, placebo-controlled double-blind trial. Intervention participants received 50 mg elemental iron for 14 weeks. SETTING The study population comprised pre-school children (n = 135) from one randomly chosen public school in the northeast of Brazil. SUBJECTS Participants were 5-year-old students from a public school. RESULTS Mean Hb and Ht values increased after iron supplementation, with p < 0.0001. There was no statistically significant increase in the placebo group. After intervention, anemia prevalence reduced only in the intervention group, from 48.0% to 26.0%. CONCLUSIONS Weekly iron supplementation was effective in reducing anemia in 5-year-olds.