K. Toussaint, X. C. Yang, Mike Zielinski
Dec 1, 2010
Citations
4
Influential Citations
127
Citations
Quality indicators
Journal
Journal of Clinical Pharmacy and Therapeutics
Abstract
What is known and background: Although paracetamol (acetaminophen), N‐(4‐Hydroxyphenyl)acetamide, is one of the world’s most widely used analgesics, the mechanism by which it produces its analgesic effect is largely unknown. This lack is relevant because: (i) optimal pain treatment matches the analgesic mechanism to the (patho)physiology of the pain and (ii) modern drug discovery relies on an appropriate screening assay.