Raquel de Oliveira Lopes, Joyce Benzaquem Ribeiro, A. S. D. Miranda
May 20, 2014
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron
Abstract
Abstract Several microorganism strains were used to reduce 2,2,2-trifluoroacetophenone ( 1 ) and 4′-Br-2,2,2-trifluoroacetophenone ( 3 ). Immobilized cells of Geotrichum candidum in calcium alginate led to conversion and enantiomeric excess higher than 99%. By using immobilized G. candidum cells under continuous flow conditions, the same conversion and enantiomeric excess were achieved in 90 min of residence time.