Terry P Lebold, Andrew B. Leduc, M. Kerr
Jul 28, 2009
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Influential Citations
109
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Quality indicators
Journal
Organic letters
Abstract
The reaction of benzyl-protected propargyl amines and 1,1-cyclopropane diesters in the presence of catalytic Zn(NTf(2))(2) allows access to highly functionalized piperidines in excellent yields. The process proceeds via a tandem cyclopropane ring-opening/Conia-ene cyclization.