10 papers analyzed
These studies suggest that effective treatments for nail fungus include VT-1161, topical treatments, recent antifungal agents like fluconazole, itraconazole, and terbinafine, the urea paste method, and thermal therapy, with some treatments requiring accurate diagnosis and combination therapies for best results.
Nail fungus, or onychomycosis, is a common and persistent condition that affects the nails, making them thick, discolored, and brittle. Effective treatment is challenging due to the difficulty of antifungal agents reaching the embedded fungus and the slow growth of nails. This synthesis will explore various treatment options and their effectiveness based on recent research.
Systemic Antifungal Treatments:
Topical Treatments:
Combination Therapies:
Alternative and Adjunctive Therapies:
Cost-Effectiveness:
Effective treatment of nail fungus often requires a combination of systemic and topical therapies, with newer antifungal agents providing better outcomes and safety profiles. While topical treatments alone are less effective, their efficacy improves significantly when combined with nail debridement or removal. Alternative methods like thermal therapy and chemical removal also show promise. Cost considerations suggest starting with less expensive treatments and escalating to more costly options if necessary.
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