Searched over 200M research papers
10 papers analyzed
These studies suggest aging is a complex, multifaceted process involving physiological deterioration, genetic and environmental factors, and cumulative functional changes, which can be influenced by free radical reactions and advanced glycation end products.
19 papers analyzed
Aging is a complex, multifaceted process that involves a progressive decline in physiological function and an increased vulnerability to death. It is influenced by genetic, environmental, and stochastic factors, and is characterized by various biological, psychological, and social changes.
Definition and Characteristics of Aging:
Physiological and Functional Decline:
Genetic and Molecular Factors:
Theories and Mechanisms:
Primary and Secondary Aging:
Hallmarks of Aging:
Aging is a natural, inevitable process characterized by a decline in physiological function and increased susceptibility to diseases and death. It is driven by genetic, molecular, and environmental factors, and involves both intrinsic biological changes and external influences. Understanding the mechanisms and hallmarks of aging can help in developing strategies to improve health and longevity.
Most relevant research papers on this topic