10 papers analyzed
Some studies suggest aspartame is safe for human consumption at current levels, while other studies indicate potential risks such as oxidative stress, neurologic effects, and adverse neurobehavioral outcomes.
19 papers analyzed
Aspartame is a widely used artificial sweetener found in numerous food and beverage products. Since its approval by the US Food and Drug Administration (FDA) in 1981, there has been ongoing debate about its safety and potential health risks. This synthesis aims to present a cohesive analysis of the current research on whether aspartame is dangerous for human consumption.
General Safety and Regulatory Approval
Carcinogenicity
Neurological Effects
Oxidative Stress and Cellular Damage
Metabolite Concerns
Epidemiological Studies
The majority of scientific evidence suggests that aspartame is safe for human consumption at current regulatory-approved levels. While some studies indicate potential risks at very high doses, typical consumption levels do not appear to pose significant health risks. However, individuals with the rare genetic disorder phenylketonuria (PKU) should avoid aspartame due to their inability to metabolize phenylalanine. Overall, aspartame remains a widely accepted non-nutritive sweetener with no substantial evidence linking it to severe health issues in the general population.
Is Cascara sagrada safe?
Does creatine cause hair loss?
What is the impact of digital twins and simulation technologies on engineering and design?
Materials Studio simulation for the adsorption properties of CO2 molecules at the surface
How do we study and model human-computer interaction?
What are the main phenomenological critiques of biomedical psychiatric approaches to mental disorder