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These studies suggest that a larger neck circumference is associated with a higher risk of developing diabetes mellitus.
20 papers analyzed
Neck circumference (NC) has emerged as a significant marker in the study of diabetes, particularly in identifying risks associated with type 2 diabetes mellitus (T2DM) and screen-detected diabetes mellitus (SDDM). This article synthesizes findings from multiple studies to elucidate the relationship between NC and diabetes, highlighting its potential as an independent risk factor.
Recent research has identified NC as a novel risk factor for SDDM. A study conducted in the Kyiv region of Ukraine found that larger NC measurements were significantly associated with higher risks of SDDM, independent of other adipose tissue distribution indicators and thyroid gland volume (ThV). This suggests that NC could serve as a reliable marker for early diabetes detection.
Several studies have demonstrated a strong association between larger NC and the incidence of T2DM. In a cohort study involving elderly Chinese individuals, larger NC was significantly linked to an increased risk of developing T2DM in both men and women. Similarly, a study from the Korean Genome and Epidemiology Study (KoGES) found that individuals with larger NC had a higher incidence of T2DM over a 10-year follow-up period. These findings underscore the importance of NC as a predictor of T2DM.
The impact of NC on diabetes risk appears to vary between genders. In the Ukrainian study, both men and women with larger NCs showed higher risks of SDDM, but the association was more pronounced in women. The KoGES study also reported gender-specific relative risks, with women in the highest NC quartile having a significantly higher risk of developing T2DM compared to men. This gender disparity highlights the need for tailored screening strategies.
NC has also been investigated as a predictive marker for gestational diabetes mellitus (GDM). A study in Turkey found that higher NC measurements in the first trimester were associated with an increased risk of developing GDM later in pregnancy. This suggests that NC could be a useful early screening tool for GDM, potentially allowing for earlier interventions.
Neck circumference is emerging as a significant, independent risk factor for various forms of diabetes, including SDDM, T2DM, and GDM. Its predictive value is evident across different populations and genders, making it a valuable marker for early diabetes detection and prevention strategies. Further research with larger sample sizes and longer follow-up periods is needed to solidify these findings and explore the underlying mechanisms linking NC to diabetes.
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