Is Garcinia safe?

Introduction

Garcinia is a genus of tropical plants known for their medicinal properties and use in traditional medicine. Various species of Garcinia, such as Garcinia cambogia, Garcinia atroviridis, and Garcinia kola, have been studied for their potential health benefits and safety. This synthesis aims to evaluate the safety of Garcinia based on findings from multiple research papers.

Key Insights

General Safety and Non-Toxicity:
- Garcinia atroviridis fruit extract was found to be safe and non-toxic in sub-chronic toxicity studies on rats, showing no adverse effects on body weight, clinical hematology, biochemical parameters, or organ histopathology.
- Garcinia kola, traditionally used in West and Central Africa, has been recognized as safe when used in traditional doses for traditional indications.
- Garcinia cambogia extract, administered at high doses to healthy men, showed no toxicological changes or significant adverse effects, indicating its safety under the study conditions.
Potential Adverse Effects:
- Some studies have raised concerns about the potential toxicity of Garcinia cambogia, particularly in multicomponent formulations, although Garcinia itself has not been confirmed as the toxic agent.
Therapeutic Properties and Safety:
- Garcinia species are rich in bioactive compounds with various therapeutic properties, including anti-obesity, antioxidant, anti-inflammatory, and antimicrobial effects .
- The safety of Garcinia products is emphasized in product development, ensuring compliance with quality and safety standards.

Conclusion

Overall, Garcinia species, including Garcinia atroviridis, Garcinia kola, and Garcinia cambogia, are generally considered safe based on current research. While some concerns have been raised about potential toxicity, particularly in multicomponent formulations, the evidence suggests that Garcinia extracts are safe when used appropriately. The therapeutic benefits of Garcinia, combined with its safety profile, make it a valuable natural resource for medicinal use.

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Summary

Consensus Meter

Introduction

Key Insights

Conclusion

Sources and full results

Sub-chronic toxicity of Garcinia atroviridis Griff Fruit's ethanol extract on Wistar rats (Ratus norvegicus)

Garcinia atroviridis Griff fruit's ethanol extract is safe and nontoxic to body weight, clinical hematology and biochemical parameters, and ten organ histopathology in Wistar rats.

Garcinia L.: a gold mine of future therapeutics

Garcinia species have potential medicinal properties, including anti-obesity, cardioprotective, and cancer-preventive properties, but their conservation and traditional uses are crucial for their conservation and future therapeutic applications.

Garcinia fruit: in the forests and domestic orchards, the prevention of diseases of modernity

Garcinia fruit species can aid in weight control and prevent cardiovascular disorders, cancer, and diabetes mellitus, among other diseases linked to oxidative stress.

Garcinia Kola (Bitter Kola): Chemical Composition

Garcinia kola is a safe and effective traditional food and therapeutic plant with potential benefits for common human ailments.

A comprehensive scientific overview of Garcinia cambogia.

Garcinia cambogia, a popular weight-loss supplement, exhibits anti-obesity activity and other health benefits, but potential toxicity concerns remain.

Application of Phytochemical and Elemental Profiling, Chemometric Multivariate Analyses, and Biological Activities for Characterization and Discrimination of Fruits of Four Garcinia Species

Garcinia cambogia, Garcinia indica, Garcinia mangostana, and Garcinia atroviridis fruits are safe for human consumption, with Garcinia mangostana showing the highest phenolics and Garcinia cambogia having the highest flavonoids.

An overview on genus garcinia: phytochemical and therapeutical aspects

Garcinia plants contain bioactive molecules with potential therapeutic properties, including hypolipidemic effects, antioxidant, anti-inflammatory, and anti-cancer properties.

Medicinal Potential of Garcinia Species and Their Compounds

Garcinia species provide a rich natural source of compounds with valuable therapeutic properties, potentially useful in preventing and treating nontransmissible chronic diseases.

Development of Garcinia atroviridis capsule towards safe, quality and efficacious product

Garcinia atroviridis capsules show potential as a safe, quality, and efficacious weight loss aid, with potential for global market penetration.

Safety of Garcinia cambogia Extract in Healthy Men: High-Doses Administration Study I

Garcinia extract is safe for high-dose administration in healthy men, with no toxicological changes or serum testosterone changes observed.

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