9 papers analyzed
Some studies suggest Goldenseal may pose safety risks due to potential liver carcinogenicity, herb-drug interactions, and phototoxicity, while other studies indicate it is unlikely to be unsafe at prescribed doses and can offer environmental and agricultural benefits.
6 papers analyzed
Goldenseal (Hydrastis canadensis) is a popular herbal remedy traditionally used for various ailments, including digestive issues, infections, and inflammation. Despite its widespread use, concerns about its safety and efficacy have been raised, prompting scientific investigations into its potential health risks and benefits.
Genotoxicity and Carcinogenicity
Herb-Drug Interactions
Reproductive Safety
Heavy Metal Contamination
Phototoxicity
Efficacy and Therapeutic Use
The safety of goldenseal is a complex issue with several concerns. While it has traditional uses and some potential benefits, scientific evidence points to significant risks, including genotoxicity, herb-drug interactions, heavy metal contamination, and phototoxicity. Additionally, the efficacy of goldenseal for most claimed therapeutic uses is not well-supported by scientific data. Therefore, caution is advised when using goldenseal, especially in combination with other medications or in topical applications exposed to light. Further research is needed to fully understand its safety profile and therapeutic potential.
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