4 papers analyzed
Some studies suggest that nicotine sprays cause initial irritant side effects that decrease within a week, while other studies indicate a high rate of local adverse effects and increased sensitivity to motion sickness.
Nicotine replacement therapies (NRTs) such as Nicorette spray are commonly used to aid smoking cessation. While effective in helping individuals quit smoking, these therapies can have side effects, especially with long-term use. This synthesis examines the long-term side effects of Nicorette spray based on findings from multiple research studies.
Local Irritant Effects:
Systemic Side Effects:
Psychological and Physiological Effects:
Nicorette spray, both nasal and mouth formulations, is effective in aiding smoking cessation but is associated with several side effects. Local irritant effects are common initially but tend to decrease over time. Systemic side effects such as dizziness and nausea are dose-dependent and can be exacerbated by motion. Psychological and physiological symptoms are generally reduced in the short term but may persist or change over longer periods. Further studies are needed to optimize dosage and minimize side effects for better long-term compliance and success rates.
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