5 papers analyzed
These studies suggest that AST (Astaxanthin) is neuroprotective due to its anti-inflammatory, antioxidative, and anti-apoptotic properties, as well as its ability to protect against glutamate-induced cytotoxicity and apoptosis.
Astaxanthin (AST) is a carotenoid known for its potent antioxidant properties. Recent research has explored its potential neuroprotective effects, particularly in the context of neurodegenerative diseases and brain injuries. This synthesis aims to consolidate findings from multiple studies to determine whether AST exhibits neuroprotective properties.
Anti-inflammatory and Antioxidative Properties:
Anti-apoptotic Effects:
Reduction of Glutamate-induced Cytotoxicity:
Improvement in Mitochondrial Function:
Reduction of Neuroinflammation and Brain Injury:
Astaxanthin demonstrates significant neuroprotective effects through its anti-inflammatory, antioxidative, and anti-apoptotic properties. It effectively reduces glutamate-induced cytotoxicity, improves mitochondrial function, and mitigates neuroinflammation and brain injury. These findings suggest that AST could be a promising therapeutic agent for neurodegenerative diseases and brain injuries.
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