4 papers analyzed
These studies suggest that semaglutide's side effects include mild gastrointestinal disturbances, increased risk of biliary disease, potential decline in eGFR, and caution regarding diabetic retinopathy.
Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), is used for the treatment of type 2 diabetes. It is available in both subcutaneous and oral formulations and has been shown to improve glycemic control and induce weight loss. However, its use is associated with various side effects, which have been extensively studied in clinical trials.
Gastrointestinal Side Effects:
Diabetic Retinopathy (DR):
Kidney Function:
Gallbladder Events:
Cardiovascular Safety:
Pancreatic and Thyroid Safety:
Injection-Site and Allergic Reactions:
Semaglutide is associated with several side effects, primarily gastrointestinal disturbances and an increased risk of diabetic retinopathy and gallbladder events. However, it does not significantly increase the risk of kidney, cardiovascular, pancreatic, or thyroid adverse events. Overall, semaglutide has a favorable safety profile for patients with type 2 diabetes, with most side effects being mild and manageable.
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