What are the symptoms of Crohn's disease?

Crohn's disease is a chronic inflammatory condition primarily affecting the gastrointestinal tract, with a range of symptoms that can impact patients' quality of life.

Key insights from the research papers include:

Common symptoms of Crohn's disease include diarrhea, abdominal pain, weight loss, and fever, with these symptoms being present in the majority of patients.
Extraintestinal manifestations such as joint, skin, eye, blood, and hepatobiliary system involvement are also prevalent, with arthropathy being the most common .
Patients report that fatigue, dietary restrictions, and impaired sleep or daytime sleepiness are among the most impactful symptoms on their daily lives.
Specific to pediatric Crohn's disease, delays in puberty, growth, and bone mineral density accrual are significant concerns, highlighting the need for monitoring in young patients.
Ocular manifestations like uveitis, iritis, episcleritis, and retinal vasculitis can occur, with some potentially leading to vision loss if untreated.
The disease can cause a range of symptoms from mouth to anus, with rectal bleeding and anemia also being noted .

In conclusion, Crohn's disease presents a spectrum of symptoms that include gastrointestinal issues such as diarrhea and abdominal pain, systemic symptoms like weight loss and fever, and a variety of extraintestinal manifestations. Fatigue and sleep disturbances are significant in affecting patients' quality of life. Special attention is required for pediatric patients and those with ocular involvement to prevent long-term complications.

What are the symptoms of Crohn's disease?

Summary

Sources and full results

Clinical features and natural history of Crohn's disease.

Crohn's disease onset peaks between the second and fourth decade, with a median age of onset of 35 months, and involvement of both colon and terminal ileum is common.

Extraintestinal manifestations of Crohn’s disease

Crohn's disease patients may experience extraintestinal manifestations, such as joint pain, skin issues, and blood disorders, that require multidisciplinary treatment strategies.

Crohn's disease

Crohn's disease is a relapsing systemic inflammatory disease influenced by environmental factors and a disturbed immune response towards a diminished diversity of commensal microbiota.

Patient-Reported Impact of Symptoms in Crohn's Disease

Crohn's disease patients experience numerous symptoms, with gastrointestinal issues, fatigue, dietary restrictions, and impaired sleep being the most prevalent and impacting on their daily lives.

Crohn's disease.

Crohn's disease is a chronic inflammatory bowel disease with symptoms ranging from abdominal pain and diarrhoea, requiring familiarity among primary care physicians and gastroenterologists for effective management.

Delays in puberty, growth, and accrual of bone mineral density in pediatric Crohn's disease: despite temporal changes in disease severity, the need for monitoring remains.

Modern treatments for pediatric Crohn's disease have led to modest delays in puberty and growth failure, but the need for close monitoring of puberty status remains.

Crohn’s Disease Ocular Manifestations

Crohn's disease can cause ocular problems like uveitis, iritis, episcleritis, keratopathy, keratoconjunctivitis, and retinal vasculitis, causing vision loss and glaucoma.

Crohn's disease what we know about it, symptoms, diagnosis, treatment

Crohn's disease is a chronic disease with symptoms like diarrhoea, abdominal pain, rectal bleeding, fever, weight loss, and fatigue.

Pathophysiology of Crohn’s Disease

Crohn's disease is a chronic inflammatory bowel disease that causes abdominal pain, diarrhoea, weight loss, anaemia, and fatigue.

Crohn’s disease

Crohn's disease is a chronic gastrointestinal condition that affects the gastrointestinal tract from mouth to anus, with symptoms including diarrhoea, abdominal pain, and weight loss.

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