What are the symptoms of narcolepsy without cataplexy?

Introduction

Narcolepsy without cataplexy is a sleep disorder characterized by excessive daytime sleepiness (EDS) without the sudden loss of muscle tone triggered by emotions, known as cataplexy. Understanding the symptoms of narcolepsy without cataplexy is crucial for accurate diagnosis and effective management.

Key Insights

Excessive Daytime Sleepiness (EDS)
- EDS is the primary symptom of narcolepsy without cataplexy, characterized by an overwhelming need to sleep during the day, often leading to unintended naps .
Sleep Paralysis and Hypnagogic Hallucinations
- Patients may experience sleep paralysis, a temporary inability to move or speak while falling asleep or waking up, and hypnagogic hallucinations, vivid dream-like experiences occurring at sleep onset .
Disturbed Nocturnal Sleep
- Individuals often have fragmented nighttime sleep, with frequent awakenings and difficulty maintaining sleep throughout the night .
REM Sleep Abnormalities
- Rapid eye movement (REM) sleep abnormalities, such as shortened REM sleep latency, are common, indicating a quicker transition to REM sleep .
Automatic Behaviors
- Some patients may engage in automatic behaviors, performing routine tasks without conscious awareness, often with no memory of the activity.

Conclusion

Narcolepsy without cataplexy is primarily characterized by excessive daytime sleepiness, sleep paralysis, hypnagogic hallucinations, disturbed nocturnal sleep, REM sleep abnormalities, and sometimes automatic behaviors. These symptoms collectively impact the quality of life and require careful management to improve patient outcomes.

What are the symptoms of narcolepsy without cataplexy?

Summary

Introduction

Key Insights

Conclusion

Sources and full results

Clinical, behavioural and polysomnographic correlates of cataplexy in patients with narcolepsy/cataplexy.

High-frequency cataplexy attacks in narcolepsy/cataplexy patients involve head, jaw, and shoulder muscles more frequently, and are more likely to be triggered by emotions.

Narcolepsy with cataplexy

Narcolepsy with cataplexy is a disabling sleep disorder affecting 0.02% of adults worldwide, with symptoms ranging from severe daytime sleepiness to sudden muscle loss.

Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system.

Symptomatic narcolepsy, cataplexy, and hypersomnia are often associated with other neurological conditions, and the hypothalamus is often involved in these cases.

The clinical spectrum of narcolepsy with cataplexy: a reappraisal

Narcolepsy with cataplexy is distinct from non-narcolepsy hypersomnia, with two distinct symptom complexes: excessive daytime sleepiness and sleep paralysis/hallucinations.

Excessive daytime sleepiness and the pathophysiology of narcolepsy-cataplexy: a laboratory perspective.

Narcolepsy-cataplexy is characterized by excessive daytime sleepiness, which represents a slow waxing and waning of alertness rather than punctate microsleeps, and may be considered a disease of state boundary control.

Cataplexy features in childhood narcolepsy

Childhood narcolepsy patients show a variety of cataplexy features, including falls, knee, head, and jaw involvement, and a previously unrecognized condition called cataplectic facies.

Narcolepsy with cataplexy.

Narcolepsy with cataplexy is a serious chronic neuropsychiatric disorder that disrupts social, educational, and vocational development, and provides insights into the mechanisms regulating human sleep.

NATURAL HISTORY, SYMPTOMS AND TREATMENT OF THE NARCOLEPTIC SYNDROME

Narcolepsy symptoms often begin in adolescence or early adult life, with cataplexy, sleep paralysis, and frequent dreams as common symptoms, and can be effectively managed with a combination of amphetamines and imipramine.

Comparison of clinical characteristics among narcolepsy with and without cataplexy and idiopathic hypersomnia without long sleep time, focusing on HLA-DRB1( )1501/DQB1( )0602 finding.

In narcolepsy without cataplexy, HLA-positivity may affect hypersomnia severity and REM propensity, while the NA w/o CA HLA-negative group and idiopathic hypersomnia without long sleep time exhibit equivalent hypersomnia severity.

High pain frequency in narcolepsy with cataplexy.

Chronic pain is significantly more common and disabling in narcolepsy with cataplexy patients, impacting sleep quantity, depression, and quality of life.

Try another search

What are the symptoms of narcolepsy without cataplexy?

Summary

Introduction

Key Insights

Conclusion

Sources and full results

Clinical, behavioural and polysomnographic correlates of cataplexy in patients with narcolepsy/cataplexy.

High-frequency cataplexy attacks in narcolepsy/cataplexy patients involve head, jaw, and shoulder muscles more frequently, and are more likely to be triggered by emotions.

Narcolepsy with cataplexy

Narcolepsy with cataplexy is a disabling sleep disorder affecting 0.02% of adults worldwide, with symptoms ranging from severe daytime sleepiness to sudden muscle loss.

Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system.

Symptomatic narcolepsy, cataplexy, and hypersomnia are often associated with other neurological conditions, and the hypothalamus is often involved in these cases.

The clinical spectrum of narcolepsy with cataplexy: a reappraisal

Narcolepsy with cataplexy is distinct from non-narcolepsy hypersomnia, with two distinct symptom complexes: excessive daytime sleepiness and sleep paralysis/hallucinations.

Excessive daytime sleepiness and the pathophysiology of narcolepsy-cataplexy: a laboratory perspective.

Narcolepsy-cataplexy is characterized by excessive daytime sleepiness, which represents a slow waxing and waning of alertness rather than punctate microsleeps, and may be considered a disease of state boundary control.

Cataplexy features in childhood narcolepsy

Childhood narcolepsy patients show a variety of cataplexy features, including falls, knee, head, and jaw involvement, and a previously unrecognized condition called cataplectic facies.

Narcolepsy with cataplexy.

Narcolepsy with cataplexy is a serious chronic neuropsychiatric disorder that disrupts social, educational, and vocational development, and provides insights into the mechanisms regulating human sleep.

NATURAL HISTORY, SYMPTOMS AND TREATMENT OF THE NARCOLEPTIC SYNDROME

Narcolepsy symptoms often begin in adolescence or early adult life, with cataplexy, sleep paralysis, and frequent dreams as common symptoms, and can be effectively managed with a combination of amphetamines and imipramine.

Comparison of clinical characteristics among narcolepsy with and without cataplexy and idiopathic hypersomnia without long sleep time, focusing on HLA-DRB1( *)1501/DQB1( *)0602 finding.

In narcolepsy without cataplexy, HLA-positivity may affect hypersomnia severity and REM propensity, while the NA w/o CA HLA-negative group and idiopathic hypersomnia without long sleep time exhibit equivalent hypersomnia severity.

High pain frequency in narcolepsy with cataplexy.

Chronic pain is significantly more common and disabling in narcolepsy with cataplexy patients, impacting sleep quantity, depression, and quality of life.

Try another search

Comparison of clinical characteristics among narcolepsy with and without cataplexy and idiopathic hypersomnia without long sleep time, focusing on HLA-DRB1( )1501/DQB1( )0602 finding.