9 papers analyzed
These studies suggest that NAD+ boosters are generally safe and may offer various health benefits, particularly for age-related diseases, mental concentration, metabolic syndrome, and liver health, with a low incidence of side effects.
5 papers analyzed
Nicotinamide adenine dinucleotide (NAD+) is a crucial coenzyme involved in various cellular processes, including energy metabolism, DNA repair, and cell survival. As NAD+ levels decline with age, there has been growing interest in NAD+ boosters, such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), to potentially mitigate age-related diseases and improve overall health. This synthesis examines the safety of NAD+ boosters based on recent research findings.
Safety and Tolerability in Humans:
Efficacy in Increasing NAD+ Levels:
Potential Health Benefits:
Mechanisms of Action:
Overall, NAD+ boosters such as nicotinamide riboside and nicotinamide mononucleotide appear to be safe for human consumption, with no serious adverse effects reported in clinical trials. These supplements effectively increase NAD+ levels and offer potential health benefits, particularly in improving metabolic functions and reducing age-related decline. However, minor side effects have been noted, and further research is needed to fully understand the long-term safety and efficacy of these supplements.
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