3 papers analyzed
These studies suggest that elevated serum carboxymethyl lysine (CML) levels are associated with atherosclerosis and may serve as a biomarker for coronary heart disease.
Atherosclerosis, a leading cause of cardiovascular diseases, is characterized by the formation of atherosclerotic plaques in the arteries. Advanced glycation end products (AGEs), such as Nε-(carboxymethyl)-lysine (CML), have been implicated in the pathogenesis of vascular diseases, including atherosclerosis. This synthesis aims to evaluate the role of serum CML in the development and progression of atherosclerosis.
Elevated Serum CML in Atherosclerosis Patients:
CML as a Biomarker for Atherosclerosis:
Correlation with Other Risk Factors:
The collective findings from the research papers indicate that elevated serum CML levels are associated with the development and progression of atherosclerosis. CML can serve as a potential biomarker for atherosclerosis, reflecting the underlying glycoxidation and lipoxidation processes. These insights underscore the importance of monitoring serum CML levels in patients at risk for or suffering from coronary heart disease.
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