Is Horny Goat Weed safe?

Introduction

Horny Goat Weed (Epimedium spp.) is a traditional herbal remedy often used for enhancing sexual function and treating erectile dysfunction. The active compound in Horny Goat Weed, icariin, has been the subject of various studies to evaluate its efficacy and safety. This synthesis aims to provide a cohesive understanding of the safety profile of Horny Goat Weed based on recent research findings.

Key Insights

Neurotrophic and Erectile Function Benefits:
- Icariin, the active component of Horny Goat Weed, has shown potential neurotrophic effects and improved erectile function in animal models. Rats treated with icariin demonstrated higher intracavernous pressure and better penile tissue health compared to controls.
Adverse Psychological Effects:
- The use of Horny Goat Weed, especially when purchased online as part of unlicensed sexual enhancement products, has been associated with adverse psychological effects such as mood changes, anxiety, hallucinations, and addictive behaviors. This raises significant public health concerns, particularly for individuals with pre-existing psychiatric conditions.
Fertility and Hormonal Benefits:
- In male rats exposed to cadmium chloride, Horny Goat Weed improved liver and renal function, lipid profiles, antioxidant enzyme activity, and sex hormone levels. This suggests potential benefits for male fertility and overall sexual health when used in moderation.

Conclusion

Horny Goat Weed, particularly its active compound icariin, shows promise in enhancing erectile function and improving sexual health markers in animal studies. However, its use, especially in unregulated forms available online, can lead to significant psychological side effects. While moderate use may offer benefits, caution is advised due to the potential for adverse effects, particularly in individuals with psychiatric conditions. Further research and regulation are necessary to ensure its safe use.

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Is Horny Goat Weed safe?

Summary

Introduction

Key Insights

Conclusion

Sources and full results

Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo.

Icariin, a compound found in horny goat weed, may have neurotrophic effects in addition to its known phosphodiesterase type 5 inhibitory effects, potentially benefiting erectile dysfunction treatment.

Sexual Enhancement Products for Sale Online: Raising Awareness of the Psychoactive Effects of Yohimbine, Maca, Horny Goat Weed, and Ginkgo biloba

Sexual enhancement products containing yohimbine, maca, horny goat weed, and Ginkgo biloba are uncontrolled online and may contain harmful substances, posing a major public health concern.

Potential Effects of Horny Goat Weed (Epimedium grandiflorum) on The Level of Fertility in Male Rats Infected with Cadmium Chloride: Biochemical and Histopathological Study

Moderate use of horny goat weed may improve male sexual performance and is considered a natural sexual stimulant.

Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed

Icariin, a component of Horny Goat Weed, shows promising anti-atherosclerotic properties through multiple mechanisms, including DNA damage, endothelial dysfunction, and platelet activation.

Icariin inhibits atherosclerosis progress in Apoe null mice by downregulating CX3CR1 in macrophage.

Icariin, a component from Horny Goat Weed, inhibits atherosclerosis progression by downregulating CX3CR1 expression in macrophages.

The effectiveness of clove oil and two different cautery disbudding methods on preventing horn growth in dairy goat kids

BUDOFF is the most effective method for preventing horn growth in dairy goat kids compared to CLOVE and BUDON.

Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives

Icariin and its derivatives show potential for developing new anti-cancer drugs, targeting cancer stem cells and drug-resistant cancer cells through various mechanisms.

Study of disbudding goat kids following injection of clove oil essence in horn bud region

Injection of clove essence effectively stops horn growth in goat kids without adverse effects on clinical parameters.

Assessment of phytotoxic action of Ageratum conyzoides L. (billy goat weed) on weeds

Ageratum conyzoides L. (billy goat weed) leaves effectively inhibit weed growth in paddy fields, potentially reducing reliance on synthetic herbicides.

Ageratum conyzoides L. for the management of pests and diseases by small holder farmers

Ageratum conyzoides L., commonly known as billygoat weed, has insecticidal and anti-microbial properties, making it a viable and economically viable alternative to synthetic pesticides for smallholder farmers.

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