How much Astragalus should I take daily?

Astragalus, a traditional herb used in Chinese medicine, has been the subject of various studies to determine its safe and effective dosage for different applications and species.

Subchronic toxicity studies in rats and dogs suggest a safe dosage range of 5.7-39.9g/kg for rats and 2.85-19.95g/kg for beagle dogs, which translates to approximately 70 or 35 times the human dosage (0.57g/kg), respectively.
Research on early weaned yak calves indicates that Astragalus root extract at a dosage of 5% to 8% of dry matter intake (DMI) can improve growth performance, antioxidant capacity, and immunity.
Studies on Tibetan sheep show that Astragalus membranaceus root supplementation at levels of 20, 50, and 80g/kg DM intake can enhance growth performance, rumen fermentation, and immunity, with 50 and 80g/kg showing the most promising results.
In dairy bull calves, supplementation with 5g and 10g Astragalus polysaccharides daily improved feed intake and daily gain, with 5g daily being the most cost-effective dosage.
For weaned pigs, dietary supplementation of Astragalus polysaccharides showed improved growth performance and immune function, with an optimal level between 381 mg/kg and 568 mg/kg for maximal average daily gain (ADG).
In immunosuppressive dogs, Astragalus Polysaccharide dosages of 50 mg/kg, 100 mg/kg, and 200 mg/kg enhanced cellular immunity, with 200 mg/kg significantly increasing immune parameters.
A botanical extract containing Astragalus membranaceus was found to be safe at an intake level of 0.5 mg/kg body weight per day for adults, excluding pregnant women, corresponding to a maximum daily intake of 35 mg.

In conclusion, the safe and effective daily dosage of Astragalus varies depending on the species and the desired health outcomes. For humans, a maximum daily intake of 35 mg has been deemed safe, while animal studies suggest a range of dosages that improve growth performance and immune function. It is important to note that these dosages are derived from controlled studies and should be adapted to individual needs and conditions under the guidance of a healthcare professional.

How much Astragalus should I take daily?

Summary

Sources and full results

Subchronic toxicity studies of Radix Astragali extract in rats and dogs.

Radix Astragali extract (RAE) is safe with a safety dosage range of 5.7-39.9g/kg for rats and 2.85-19.95g/kg for beagle dogs, equivalent to 70 or 35 times of human doses.

Astragalus root extract improved average daily gain, immunity, antioxidant status and ruminal microbiota of early weaned yak calves.

Astragalus root extract supplementation at 5% to 8% DMI improves growth performance, antioxidant capacity, and immunity in early weaned yak calves.

Astragalus membranaceus root supplementation improves average daily gain, rumen fermentation, serum immunity and antioxidant indices of Tibetan sheep.

Astragalus membranaceus root supplementation in Tibetan sheep feed improves growth performance, rumen fermentation, and enhances immunity, with 50 and 80 g/kg showing the most promising results.

Effect of Different Astragalus Polysaccharides Levels in Diets on Growth Performance in Dairy Bull Calf

Adding 5g Astragalus polysaccharides to dairy bull calves' diets every day significantly improves feed intake, daily gain, reduces diarrhea rates, and increases body size indicators.

Effects of dietary Astragalus polysaccharide on growth performance and immune function in weaned pigs

Dietary Astragalus polysaccharide (APS) can improve growth performance and immune function in weaned pigs, with optimal levels between 381 mg/kg and 568 mg/kg for maximal ADG and 324 to 563 mg/kg for immune responses.

Effects of Astragalus Polysaccharides on Associated Immune Cells and Cytokines in Immunosuppressive Dogs

Astragalus polysaccharides at 200 mg/kg significantly enhance the cellular immune level in immunosuppressive dogs, providing evidence for their development as companion animal health products and clinical applications.

Safety of a botanical extract derived from Panax notoginseng and Astragalus membranaceus (AstraGin™) as a novel food pursuant to Regulation (EU) 2015/2283

The EFSA Panel on Nutrition, Novel Foods, and Food Allergens found that AstraGinTM, a botanical extract derived from Panax notoginseng and Astragalus membranaceus, is safe for consumption at a maximum daily intake of 35 mg for adults excluding pregnant women

[Effects of large dose of Astragalus membranaceus on the dendritic cell induction of peripheral mononuclear cell and antigen presenting ability of dendritic cells in children with acute leukemia].

Large dose of Astragalus can increase dendritic cell induction and enhance antigen presenting ability in children with acute leukemia.

Dietary supplementation with Astragalus polysaccharide enhances ileal digestibilities and serum concentrations of amino acids in early weaned piglets

Dietary supplementation with Astragalus polysaccharide enhances growth performance and increases amino acid digestibilities in early weaned piglets, potentially improving their overall health.

Effects of Astragalus membranaceus root processed to different particle sizes on growth performance, antioxidant status, and serum metabolites of broiler chickens.

Dietary supplementation of Astragalus membranaceus root powder enhances serum antioxidant status in broiler chickens, but has no effect on growth performance.

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