How Much Gymnema Sylvestre Should I Take Daily?

Introduction

Gymnema sylvestre is a plant traditionally used for managing diabetes and various other health conditions. Determining the appropriate daily intake is crucial for its safe and effective use.

Key Insights from Research Papers

Gymnema sylvestre at doses of 300 mg/kg and 600 mg/kg body weight (BW) in rats showed potential toxicity, affecting liver and kidney function as well as hematological parameters, suggesting that lower doses may be safer for consumption.
A safe dose identified in the study for Gymnema sylvestre was 100 mg/kg BW or below, as it did not significantly alter biochemical and hematological parameters in rats.
The content of gymnemic acid, an active component of Gymnema sylvestre, varied widely in commercial health products, ranging from non-detectable levels to 20.5 mg/g in tablets and other forms.

Conclusion

The research indicates that Gymnema sylvestre should be consumed at lower doses to avoid potential toxicity, with 100 mg/kg body weight per day identified as a safe threshold in animal studies. However, the actual content of active components like gymnemic acid can vary significantly in commercial products, which should be taken into consideration when determining the appropriate dosage for human consumption.

Summary

Not a yes or no question

Introduction

Key Insights from Research Papers

Conclusion

Sources and full results

Acute and sub-acute toxicity profile of crude extract and fractions of Gymnema sylvestre

Contents of Gymnemic Acid in Health Foods Using Gymnema sylvestre

Fecal steroid excretion is increased in rats by oral administration of gymnemic acids contained in Gymnema sylvestre leaves.

Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients.

[Gymnema sylvestre leaf extract: a 52-week dietary toxicity study in Wistar rats].

A systematic review of Gymnema sylvestre in obesity and diabetes management.

Effect of Gymnema sylvestre Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion.

In vitro callus and in vivo leaf extract of Gymnema sylvestre stimulate β-cells regeneration and anti-diabetic activity in Wistar rats.

A novel dihydroxy gymnemic triacetate isolated from Gymnema sylvestre possessing normoglycemic and hypolipidemic activity on STZ-induced diabetic rats.

Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of Gymnema sylvestre

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