10 papers analyzed
Some studies suggest that Phenibut can be safe and well-tolerated at therapeutic doses, while other studies indicate that it has potential for abuse, dependence, withdrawal, and serious adverse effects, especially when used inappropriately or combined with other substances.
11 papers analyzed
Phenibut is a psychoactive substance that acts on GABAB receptors and has been used for its anxiolytic and nootropic effects. Its safety profile has been questioned due to reports of dependence, intoxication, and withdrawal symptoms, particularly when obtained online and used in doses exceeding recommended therapeutic levels.
While phenibut can be safe at therapeutic doses under clinical supervision, there is substantial evidence of its potential for abuse, dependence, and serious adverse effects, especially when used in high doses or obtained from unregulated online sources. The discrepancy between the safety profile in clinical settings and the risks associated with recreational use or self-medication underscores the need for caution and regulation.
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