6 papers analyzed
These studies suggest that Rift Valley fever can be treated with antiviral drugs like ribavirin, poly(ICLC), sorafenib, and favipiravir, as well as with convalescent plasma and effective vaccination, but there is also a need for more antiviral treatments due to varying severity based on exposure method.
Rift Valley fever (RVF) is a significant zoonotic disease caused by the Rift Valley fever virus (RVFV), which can lead to severe health complications in both humans and animals. Despite the absence of FDA-approved therapeutics specifically for RVFV, research has explored various treatment strategies.
The treatment of Rift Valley fever involves the use of antiviral drugs such as ribavirin and favipiravir, which have shown promise in animal studies. Additionally, repurposing existing FDA-approved drugs like sorafenib could provide new therapeutic avenues. However, the effectiveness of these treatments may be influenced by factors such as the route of viral exposure. The development of vaccines remains a critical goal for the long-term control of RVF.
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