6 papers analyzed
These studies suggest that longevity is influenced by genetic factors, particularly those related to metabolism, oxidative stress resistance, and population-specific genes, with implications for aging, cardiovascular health, and potential anti-aging therapies.
6 papers analyzed
Research into the determinants of longevity has consistently pointed to a genetic component, with various studies exploring how genetic factors interact with environmental influences to shape the aging process and life expectancy.
The synthesis of findings from multiple studies suggests that longevity is indeed influenced by genetics, with specific genes and pathways related to energy metabolism, oxidative stress resistance, and cardiovascular health playing a crucial role. However, the genetic determinants of longevity are complex and dynamic, with sex, age, and environmental interactions also being significant. The identification of longevity-associated genes remains a challenge, but the use of model organisms like mice offers promising avenues for advancing our understanding of the genetics of aging and longevity.
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