Does resistant exercise affect irisin
Pro Research Analysisby 
Searched over 200M research papers
Consensus Meter
The Impact of Resistance Exercise on Irisin Levels
Introduction to Irisin and Exercise
Irisin is a myokine, a type of protein released by muscle cells in response to physical activity. It has garnered significant attention for its potential role in mediating the beneficial effects of exercise, particularly in relation to metabolic health and insulin sensitivity. This article explores the specific impact of resistance exercise on irisin levels, drawing on findings from multiple research studies.
Resistance Exercise vs. Endurance Exercise
Research indicates that resistance exercise induces a more pronounced irisin response compared to endurance exercise. A study involving healthy males demonstrated that plasma irisin concentrations significantly increased one hour after resistance exercise, but not after endurance exercise or a combination of both. This suggests that resistance exercise might be more effective in stimulating irisin release.
Chronic Resistance Training and Irisin
Chronic resistance training also appears to elevate circulating irisin levels, particularly in older adults. A systematic review and meta-analysis of randomized controlled trials found a non-significant trend towards increased irisin levels following resistance training, with significant increases observed in older adults and when the training was demanding and progressive. Another study confirmed that 12 weeks of resistance training significantly increased serum irisin levels in older male adults, with a notable correlation between reduced body fat percentage and increased irisin levels.
Resistance Training in Different Populations
The effects of resistance training on irisin levels have been studied across various populations, including those with metabolic syndrome. In a randomized controlled trial involving overweight women with metabolic syndrome, resistance exercise did not significantly change serum irisin levels over an 8-week period. However, muscle mass increased significantly, and body fat percentage decreased across all exercise groups. This suggests that while irisin levels may not always change, resistance training still offers substantial metabolic benefits.
Mechanisms and Correlations
The mechanisms by which resistance exercise influences irisin levels are still being explored. One study on aging mice and humans found that resistance training increased irisin expression in both serum and muscle tissue, correlating positively with improvements in muscle strength and function. Additionally, irisin has been linked to improved insulin sensitivity and reduced inflammation, which are critical factors in managing metabolic disorders.
Combined Exercise Interventions
Combining resistance exercise with other forms of training, such as aerobic exercise, can also impact irisin levels. A study on males with metabolic syndrome showed that combined aerobic and resistance exercise led to more favorable changes in body composition and metabolic markers compared to aerobic exercise alone. This highlights the potential benefits of incorporating multiple exercise modalities for comprehensive health improvements.
Conclusion
In summary, resistance exercise has a significant impact on irisin levels, particularly when performed consistently and progressively. While the response may vary based on factors such as age and health status, resistance training consistently shows benefits in muscle function, body composition, and metabolic health. Further research is needed to fully understand the mechanisms and optimize exercise protocols for enhancing irisin levels and related health outcomes.
Sources and full results
Most relevant research papers on this topic
Resistance exercise induces a greater irisin response than endurance exercise.
The effects of aerobic, resistance, and combined exercises on the plasma irisin levels, HOMA-IR, and lipid profiles in women with metabolic syndrome: A randomized controlled trial
Effect of Chronic Resistance Training on Circulating Irisin: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Resistance exercise training increases the expression of irisin concomitant with improvement of muscle function in aging mice and humans
Effects of 12 Weeks Resistance Training on Serum Irisin in Older Male Adults
A Randomized Controlled Trial on the Effects of 12 Weeks of Aerobic, Resistance, and Combined Exercises Training on the Serum Levels of Nesfatin-1, Irisin-1 and HOMA-IR
The effect of exercise interventions on Irisin level: a systematic review and meta-analysis of randomized controlled trials
Molecular Basis of Irisin Regulating the Effects of Exercise on Insulin Resistance
Eccentric resistance training and β-hydroxy-β-methylbutyrate free acid affects muscle PGC-1α expression and serum irisin, nesfatin-1 and resistin in rats
Effect of Exercise Interventions on Irisin and Interleukin-6 Concentrations and Indicators of Carbohydrate Metabolism in Males with Metabolic Syndrome
Try another search
What dose of ashwagandha has been show to promote sleep?
What emerging technologies, such as virtual reality and augmented reality, have the potential to rev
Does glycine help you sleep
Does halal certification affect purchasing behavior?
What is food poisoning and what are its symptoms?
does exercise reduce the chances of dementia?