6 papers analyzed
These studies suggest that while biotin is essential for various metabolic processes and has no known toxicity at physiological levels, high doses may interfere with laboratory test results and have poorly studied potential toxic effects, especially in specific patient populations such as those with end-stage renal disease.
Vitamin B7, commonly known as biotin, is a water-soluble vitamin that plays a critical role in various metabolic processes. It serves as a coenzyme for carboxylases involved in fatty acid synthesis, gluconeogenesis, and amino acid metabolism. While biotin is essential for health, its safety, particularly in supplemental form, has been a subject of research.
Biotin is essential for human health and is typically safe when consumed through diet. However, supplementation, especially at high doses, can interfere with laboratory tests and potentially affect patient care. While biotin has no known toxicity due to its water-solubility and excretion through urine, the effects of pharmacological doses and the impact of chronic alcohol exposure on biotin uptake require further investigation. Overall, biotin is safe for most individuals, but caution is advised when considering high-dose supplements.
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