10 papers analyzed
These studies suggest that tumor treating fields (TTFields) are a promising, non-invasive treatment that disrupts cancer cell mitosis, slows tumor growth, and can be effectively combined with chemotherapy and radiotherapy, with minimal side effects.
Tumor Treating Fields (TTFields) are a novel, non-invasive cancer treatment modality that uses low-intensity, intermediate-frequency alternating electric fields to disrupt cell division and inhibit tumor growth. This treatment has shown promise in various types of cancer, particularly glioblastoma multiforme (GBM) and non-small cell lung cancer (NSCLC).
Mechanism of Action:
Clinical Efficacy:
Preclinical and In Vivo Studies:
Combination Therapies:
Tumor Treating Fields (TTFields) represent a promising and innovative approach to cancer treatment, particularly for glioblastoma multiforme and non-small cell lung cancer. By disrupting mitosis and selectively targeting dividing cells, TTFields can inhibit tumor growth with minimal systemic toxicity. Clinical and preclinical studies have demonstrated the efficacy of TTFields both as a monotherapy and in combination with other treatments, suggesting a broad potential for this modality in various cancer types. Further research and clinical trials are needed to optimize TTFields' application and fully understand their mechanisms of action.
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